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KMID : 0882420090770040498
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Korean Journal of Medicine
2009 Volume.77 No. 4 p.498 ~ p.502
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A case of cerebral thromboembolism in ulcerative colitis
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Oh Jong-Taek
Jeon Seong-Woo
Lee Eung-Kap
Lee Soon-Hak
Jung Min-Kyu
Kim Sung-Kook
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Abstract
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Although cerebral thromboembolic disease is a rare extraintestinal manifestation of ulcerative colitis, it is one of the major causes of death in patients with the disease. A 29-year-old man who had a 7-year history of ulcerative colitis was admitted to our hospital complaining of nausea, vomiting, bloody diarrhea, and colicky abdominal pain. Fourteen days after admission, he developed sudden-onset left pure motor hemiplegia. Magnetic resonance imaging and angiography revealed an infarction involving the right temporo-occipital hemisphere and diffuse middle cerebral artery territory. Neck computed tomography angiography showed no evidence of cervical carotid or vertebral artery abnormalities, and transthoracic and transesophageal echocardiograms revealed no evidence of thrombi. Factor V was elevated to 176% (normal 50~150%) and protein S antigen had decreased to 57% (normal60~150%). He was managed with antiplatelet agents and a total proctocolectomy.
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KEYWORD
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Ulcerative colitis, Cerebral infarction, Thromboembolism
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